49ers Lose Deebo Samuel to Hamstring Injury Against Seahawks

San Francisco 49ers wide receiver Deebo Samuel suffered a hamstring injury against the Seattle Seahawks on Sunday, forcing him out of Week 5 action after a third-quarter rushing play at the game. The injury affects the 49ers offense as the team awaits further details.

According to USA Today, Samuel was injured while carrying the ball on a first-and-10 play late in the third quarter. He received medical attention on the field before moving to the sideline and was ruled out for the rest of the contest.

The 49ers announced Samuel was unavailable because of the hamstring issue, according to Sporting News and Heavy. Before leaving, Samuel recorded two receptions for 21 yards and two carries for four rushing yards.

San Francisco also faced another receiver concern against Seattle, with Jacob Cowing dealing with an ankle injury and listed as questionable to return, according to USA Today.

Samuel's absence left quarterback Brock Purdy with Mike Evans, Jordan Watkins and Brandin Cooks as the remaining wide receiver options, while Christian McCaffrey and George Kittle remained available offensive contributors.

Samuel has previously dealt with hamstring problems during his NFL career. Heavy reported that a 2020 hamstring strain ended his season after he appeared in seven games and recorded 33 receptions for 391 yards and one touchdown.

The same outlet reported Samuel also missed time after a hamstring injury in October 2022. The 49ers evaluated his recovery before he returned after the team's bye week.

Kyle Shanahan addressed a previous Samuel hamstring decision during the 2022 season.

"It’s not a precaution, he’s not good enough to go," said Kyle Shanahan, head coach.

The 49ers will now determine the severity and recovery timeline of Samuel's latest injury. The team has not announced how long the receiver may be sidelined.